Host response to the presence of Helicobacter spp. DNA in the liver of patients with chronic liver diseases.

نویسندگان

  • Magda Rybicka
  • Joanna Nakonieczna
  • Piotr Stalke
  • Krzysztof Piotr Bielawski
چکیده

Literature data indicate an association between the presence of Helicobacter spp. in the liver and the development of hepatocellular carcinoma (HCC). However, the role of H. pylori infections in chronic liver diseases (CLD) remains controversial. The aim of this study was to detect Helicobacter spp. DNA in patients with CLD, and to investigate the host response to the presence of the bacterium in the liver. Helicobacter spp. DNA was detected in 59% samples. H.pylori was the most prevalent species (94%). We estimated the expression level of IL-1 and IL-8 genes. The presence of Helicobacter spp. did not have a significant effect on the gene expression of IL-8 and IL-1.

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عنوان ژورنال:
  • Polish journal of microbiology

دوره 60 2  شماره 

صفحات  -

تاریخ انتشار 2011